MicrobiologybioRxivPreprint
Redefining the role of the Plasmodium heme detoxification protein: From hemozoin formation to mitochondrial protein synthesis
Louis Sarrazin, Melissa R. Rosenthal, Joachim Kloehn…·Joachim Michael Matz
This study shows that the Plasmodium heme detoxification protein (HDP) is essential for mitochondrial protein biosynthesis, not hemozoin formation, and its loss disrupts mitochondrial function and parasite survival.
DOI 10.1101/2025.11.27.690934