Author

Melissa R. Rosenthal

University of GenevaORCID 0000-0002-4490-6010Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:plant (other)· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Daniel E. GoldbergiD· 2 shared Anna-Lena SandtmanniD· 1 shared Coralie BouletiD· 1 shared Joachim KloehniD· 1 shared Joachim Michael MatziD· 1 shared Katharina Scholz-HöhniD· 1 shared Louis SarraziniD· 1 shared Robert Domenech-EresiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersPharmacology & Toxicology

Daniel E. GoldbergORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologyeLifePeer-reviewedMar 23, 2026

4-aminoquinolines block heme iron reactivity and interfere with artemisinin action

Melissa R. Rosenthal, Daniel E. Goldberg

This study investigates drug-drug interactions between artemisinins and quinolines in malaria treatment, finding antagonistic effects and highlighting potential liabilities in combination therapies.

DOI 10.7554/elife.108976.3

plant (other)experimental assay

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MicrobiologybioRxivPreprintNov 27, 2025

Redefining the role of the Plasmodium heme detoxification protein: From hemozoin formation to mitochondrial protein synthesis

Louis Sarrazin, Melissa R. Rosenthal, Joachim Kloehn…·Joachim Michael Matz

This study shows that the Plasmodium heme detoxification protein (HDP) is essential for mitochondrial protein biosynthesis, not hemozoin formation, and its loss disrupts mitochondrial function and parasite survival.

DOI 10.1101/2025.11.27.690934

plant (other)proteomics

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