Author

Peter Yi Guan

University of North Carolina at Chapel HillORCID 0009-0000-4849-6015Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:imaging· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Research Focus:GWAS / association mapping· 1 Assay:scATAC-seq· 1

Frequent Co-Authors

Bingxin ZhaoiD· 2 shared Hongtu Zhu BiD· 2 shared Jason L. SteiniD· 2 shared Jie Chen· 2 shared Patrick F. SullivaniD· 2 shared Shuai HuangiD· 2 shared Tengfei LiiD· 2 shared Zhiwen JiangiD· 2 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersGenetic & Genomic Medicine

Bingxin ZhaoORCID

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3 papers

Recent·Most cited

Genetic & Genomic MedicineNature CommunicationsPeer-reviewedDec 23, 2025

Mapping rare protein-coding variants on multi-organ imaging traits

Yijun Fan, Jie Chen, Zirui Fan…·Bingxin Zhao

The paper identifies rare protein-coding variants associated with multi-organ MRI traits using exome-wide association analysis in the UK Biobank.

DOI 10.1038/s41467-025-67431-y

𝕏 PostBluesky

Genetic & Genomic MedicinemedRxivPreprintAug 30, 2023

The pivotal role of the X-chromosome in the genetic architecture of the human brain

Zhiwen Jiang, Patrick F. Sullivan, Tengfei Li…·Hongtu Zhu B

The paper investigates the genetic impact of the X-chromosome and sex differences in the human brain, identifying 72 genome-wide significant trait-locus pairs linked to brain-related disorders.

4 citations

𝕏 PostBluesky

BioinformaticsFrontiers in GeneticsPeer-reviewedFeb 17, 2023

Destin2: integrative and cross-modality analysis of single-cell chromatin accessibility data

Peter Yi Guan, Jin Seok Lee, Lihao Wang…·Yuchao Jiang

Destin2 improves cross-modality analysis of scATAC-seq data by integrating multiple epigenomic features for dimension reduction, clustering, and trajectory inference.

2 citations

humanscATAC-seq

𝕏 PostBluesky