Cancer BiologybioRxiv
Altered thymic niche synergistically drives the massive proliferation of malignant thymocytes
Erika Tsingos, Advaita M Dick, Baubak Bajoghli
This study combines computational modeling and in vivo experiments to show that thymic niche alterations synergize with genetic mutations to drive rapid T-ALL progression in medaka.
DOI 10.7554/elife.101137