Author

Alan Karthikesalingam

Google (United States)ORCID 0009-0000-4958-5976Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Alexander DaryiniD· 2 shared Anatoly Myaskovsky· 2 shared Anil K. PalepuiD· 2 shared Annalisa PawloskyiD· 2 shared Juraj GottweisiD· 2 shared Tao TuiD· 2 shared Vivek NatarajaniD· 2 shared Wei‐Hung WengiD· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Alexander DaryinORCID

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2 papers

Recent·Most cited

BioinformaticsAdvanced SciencePeer-reviewedSep 14, 2025

AI-assisted Drug Re-purposing for Human Liver Fibrosis

Yuan Guan, Lu Cui, Jakkapong Inchai…·Gary Peltz

This study uses an AI co-scientist to identify and validate anti-fibrotic drugs in human hepatic organoids, finding that epigenomic modifiers play a key role in liver fibrosis.

19 citationstop 1%

humanbulk RNA-seq

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MicrobiologyCellPeer-reviewedSep 9, 2025

AI mirrors experimental science to uncover a novel mechanism of gene transfer crucial to bacterial evolution

José R. Penadés, Juraj Gottweis, Lingchen He…·Tiago R. D. Costa

This paper tests an AI's ability to generate hypotheses about bacterial gene transfer mechanisms, finding it matches experimentally confirmed results.

42 citationstop 1%

bacteria (other)machine learning (classical)

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