Author

Alexander Daryin

Google (Switzerland)ORCID 0000-0002-7549-9702Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Alan KarthikesalingamiD· 2 shared Anatoly Myaskovsky· 2 shared Anil K. PalepuiD· 2 shared Annalisa PawloskyiD· 2 shared Juraj GottweisiD· 2 shared Tao TuiD· 2 shared Vivek NatarajaniD· 2 shared Wei‐Hung WengiD· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Alan KarthikesalingamORCID

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2 papers

Recent·Most cited

AI-assisted Drug Re-purposing for Human Liver Fibrosis

Yuan Guan, Lu Cui, Jakkapong Inchai, Zhuoqing Fang, Jacky Law, Alberto Alonzo Garcia Brito, Annalisa Pawlosky, Juraj Gottweis, Alexander Daryin, Anatoly Myaskovsky, Lakshmi Ramakrishnan, Anil K. Palepu, Kavita Kulkarni, Wei‐Hung Weng, Zhuanfen Cheng, , Gary Peltz

This study uses an AI co-scientist to identify and validate anti-fibrotic drugs in human hepatic organoids, finding that epigenomic modifiers play a key role in liver fibrosis.

Advanced Science · Sep 14, 2025Peer-reviewedBioinformatics

AI mirrors experimental science to uncover a novel mechanism of gene transfer crucial to bacterial evolution

José R. Penadés, Juraj Gottweis, Lingchen He, Jonasz B. Patkowski, Alexander Daryin, Wei‐Hung Weng, Tao Tu, Anil K. Palepu, Anatoly Myaskovsky, Annalisa Pawlosky, Vivek Natarajan, Alan Karthikesalingam, Tiago R. D. Costa

This paper tests an AI's ability to generate hypotheses about bacterial gene transfer mechanisms, finding it matches experimentally confirmed results.

Cell · Sep 9, 2025Peer-reviewedMicrobiology