Author

Ashley Helmuth

Yale UniversityORCID 0009-0000-6124-666XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Approach:experimental assay· 2 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Assay:scATAC-seq· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Hattie ChungiD· 2 shared Alex K. ShalekiD· 1 shared Alison KochersbergeriD· 1 shared Andrew Minagar· 1 shared Benedikt ObermayeriD· 1 shared Caleb A. LareauiD· 1 shared David CapperiD· 1 shared David S. FischeriD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenomics

Hattie ChungORCID

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2 papers

Recent·Most cited

GenomicsNature AgingPeer-reviewedJun 17, 2026

Aging disrupts spatiotemporal coordination in the cycling murine ovary

Tammy C. T. Lan, Alison Kochersberger, Ruth Raichur…·Hattie Chung

This study uses spatial transcriptomics to show that aging disrupts spatial and temporal coordination of folliculogenesis in mouse ovaries, leading to tissue disorganization and reproductive decline.

13 citationstop 1%

mousespatial transcriptomics

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Systems BiologybioRxivPreprintSep 17, 2025

Cryo-mtscATAC-seq for single-cell mitochondrial DNA genotyping and clonal tracing in archived human tissues

Maren Salla, Benedikt Obermayer, Marie Cotta…·Leif S. Ludwig

The paper introduces Cryo-mtscATAC-seq to genotype mitochondrial DNA and trace clones in frozen human tissues, revealing clonal patterns in various diseases.

2 citations

humanscATAC-seq

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