Author

Sara D. Irish

University of East AngliaORCID 0009-0000-6824-3445Unclaimed ORCID profile · follow to get notified of new preprints

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Evolutionary Biology· 1

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Organism:C. elegans· 1 Approach:statistical model· 1

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A Jordan Kimberley· 1 shared Alexei A. MaklakoviD· 1 shared Jacob A. MooradiD· 1 shared Simone ImmleriD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperEvolutionary Biology

A Jordan Kimberley

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1 paper

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Evolutionary BiologybioRxivPreprintJun 18, 2025

Mutation accumulation underpins evolution of lifespan extension by dietary restriction

Sara D. Irish, A Jordan Kimberley, Simone Immler…·Alexei A. Maklakov

This study shows that dietary restriction extends lifespan in C. elegans by suppressing fertility, not through adaptive hypotheses, and suggests mutation accumulation drives this evolutionary effect.

2 citations

C. elegansstatistical model

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