Bert van Erp

This study shows that the archaeal histone HTkC forms highly compact DNA structures, doubling the compaction level of hypernucleosomes and highlighting its role in chromatin organization.

This study investigates how Mg2+ ions affect the structure and stability of hypernucleosomes formed by archaeal histones from T. kodakarensis, showing distinct effects compared to previously characterized histones.

The paper uses AlphaFold2 to classify prokaryotic histones into 17 groups and identifies a new histone superfamily that bridges DNA instead of wrapping it.