Author

Sara Sadat Afjeh

Centre for Addiction and Mental HealthORCID 0009-0000-7625-2333Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Andreea Oliviana DiaconescuiD· 1 shared Clement C.H. ZaiiD· 1 shared Daniel FelskyiD· 1 shared Fernanda C. Dos SantosiD· 1 shared James L. KennedyiD· 1 shared Mahbod EbrahimiiD· 1 shared Mohamed AbdelhackiD· 1 shared Niki AkbarianiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Andreea Oliviana DiaconescuORCID

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1 paper

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintAug 4, 2026

Investigating the Causal Relationship between Neuroticism and Alzheimer's Disease Using Mendelian Randomization and the Mediating Role of Modifiable Risk Factors

Niki Akbarian, Mahbod Ebrahimi, Fernanda C. Dos Santos…·James L. Kennedy

This study uses Mendelian randomization and mediation analysis to show that neuroticism's link to Alzheimer's disease is mediated by modifiable factors like depression, hypertension, and alcohol consumption, rather than being causal.

DOI 10.64898/2026.08.01.26359481

humanGWAS summary statistics

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