Bowei Ye

CHROME improves regulatory genomics predictions by integrating physically validated chromatin interactions into graph models, enhancing accuracy and interpretability for ChIP-seq, eQTL, and variant pathogenicity.

G-SPRI predicts cancer driver events from missense mutations by integrating structural and mutation-specific features using a graph model.

ChromPolymerDB reconstructs single-cell 3D chromatin structures from bulk Hi-C data and provides a database for analyzing chromatin conformation across 50 human cell types.

CASTpFold extends the CASTp tool to provide accurate and comprehensive protein surface topography analysis using AlphaFold2 structures and functional annotations.