Author

Tim Thierer

Research Institute of Molecular PathologyORCID 0009-0000-8689-1366Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Organism:yeast· 1

Frequent Co-Authors

Karl MechtleriD· 2 shared Manuel MatzingeriD· 2 shared Julia LeodolteriD· 1 shared Micha Johannes BirklbaueriD· 1 shared Viktoria DorferiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 8 mutual co-author links

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2 shared papersBiochemistry

Karl MechtlerORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintOct 21, 2026

Making the Impossible Possible: Uniting TMT and DIA for Scalable Low-Input-Proteomics

Tim Thierer, Micha Johannes Birklbauer, Viktoria Dorfer…·Manuel Matzinger

This paper combines TMT and DIA proteomics techniques to improve low-input proteomics, showing how to overcome co-isolation interference and enabling TMT quantification with DIA-focused software.

DOI 10.64898/2026.10.20.760427

humanyeast

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Systems BiologybioRxivPreprintApr 13, 2026

Pushing the limits of SCP: bacSCP, a proof-of-concept study to investigate heterogeneity of bacteria by single cell proteomics.

Julia Leodolter, Tim Thierer, Karl Mechtler, Manuel Matzinger

This study introduces bacSCP, a single-cell proteomics protocol for bacteria, demonstrating its ability to quantify proteins and reveal stress-response heterogeneity in Bacillus subtilis.

1 citation

bacteria (other)proteomics

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