Author

William O'Brien

University of California, Los AngelesORCID 0009-0000-9465-1303Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Assay:metagenomics· 1 Research Focus:software / tool· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Eleazar EskiniD· 2 shared Seungmo LeeiD· 2 shared Vivek Agarwal· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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2 shared papersGenomics

Eleazar EskinORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintSep 24, 2026

taxutils: Tools for managing and operating on NCBI taxonomy and accession mappings

William O'Brien, Seungmo Lee, Vivek Agarwal, Eleazar Eskin

The paper introduces taxutils, a tool for managing NCBI taxonomy and accession mappings, and demonstrates its use in assessing assembly quality through taxonomic mapping analysis.

DOI 10.64898/2026.09.18.752821

experimental assaysoftware / tool

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BioinformaticsbioRxivPreprintAug 6, 2026

TDKC (Target Distilled K-mer Classifier): Ultrafast and Memory-Efficient Sequence Classification for Target Pathogen Diagnostics

Seungmo Lee, Vivek Agarwal, William O'Brien, Eleazar Eskin

TDKC improves metagenomic pathogen detection by reducing memory and computational costs while maintaining accuracy.

DOI 10.64898/2026.06.05.730319

metagenomicsstatistical model

𝕏 PostBluesky