Xiaoyu Jenny Yang

This study identifies FRMD8 as a regulator of tmTNF-α processing in breast cancer metastasis, showing its role in modulating ADAM17 activity and TNF-α dynamics.

This study shows that tumoroids from six cancer types can be maintained long-term in a standardized serum-free medium, preserving their genetic and phenotypic features.

This paper introduces scPRS, a deep learning model that deconvolves polygenic risk scores at the single-cell level to uncover cellular and molecular disease mechanisms in complex human diseases.