Synthetic BiologyProceedings of the National Academy of SciencesPeer-reviewed
Definitive demonstration by synthesis of genome annotation completeness
Paul R. Jaschke, Gabrielle A. Dotson, Kay Su Hung…·Drew Endy
The paper demonstrates genome annotation completeness for bacteriophage oX174 by synthesizing mutant genomes and showing no new genes are encoded beyond known essential and cryptic ORFs.
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