Learning from tandem mass spectra at scale with a self-supervised foundation model for proteomics
Mechiel Nieuwoudt, Marco Reverenna, Divanisha Patel, Rachel Catzel, Isaac H.J. Houngue, Jemma Daniel, Kevin Eloff, Alberto Santos, Nicolás López Carranza, Timothy P. Jenkins, Jeroen Van Goey, Konstantinos Kalogeropoulos
This paper introduces InstaNovo-FM, a self-supervised foundation model for proteomics that learns from tandem mass spectra to enable transferable applications across datasets and instruments.
bioRxiv · Sep 8, 2026 · PreprintBioinformatics