MicrobiologyRNAPeer-reviewed
Understanding off-target growth defects introduced to influenza A virus by synonymous recoding
Colin Sharp, Beth Thompson, Ananya Ferdous Hoque…·Eleanor R. Gaunt
This study identifies compensatory mutations that cause replication defects in a CpG-enriched influenza A virus, revealing polymerase slippage and type I interferon induction as key mechanisms.
7 citations