Investigating the evolutionary plasticity of influenza virus splicing using influenza A virus segment 7 as a model system
周恕, Colin Sharp, Eleanor R. Gaunt, Rute Maria Pinto, Paul Digard
This study investigates the evolutionary flexibility of influenza A virus splicing by testing mutations in SD and SA sites, finding that small changes can activate alternative splicing and produce viable variants with altered ion channel and M1 proteins.
bioRxiv · Oct 23, 2026 · PreprintMicrobiology