Prashant Sohani

The paper expands the AlphaFold Protein Structure Database to include proteome-scale quaternary structures, predicting 1.81M high-confidence protein complexes and revealing conserved structural clusters across domains of life.

The paper accelerates protein structure prediction using OpenFold with TensorRT and MMseqs2-GPU, achieving 131x faster inference than AlphaFold2 on specific hardware.