Alejandro Chacón

The paper expands the AlphaFold Protein Structure Database to include proteome-scale quaternary structures, predicting 1.81M high-confidence protein complexes and revealing conserved structural clusters across domains of life.

The paper accelerates protein structure prediction using OpenFold with TensorRT and MMseqs2-GPU, achieving 131x faster inference than AlphaFold2 on specific hardware.

The paper introduces GPU-accelerated homology search with MMseqs2, achieving faster sequence similarity detection than CPU methods and improving structure prediction speeds.

Parabricks accelerates genomic analysis using GPU acceleration, reducing processing time while maintaining accuracy across various sequencing modalities.

CUDASW++4.0 improves protein sequence database search speed using GPU-based Smith-Waterman alignment with performance gains over previous methods and CPU tools.