Author

Mustafa Obeid

Hebrew University of JerusalemORCID 0009-0001-1225-9007Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Rami I. AqeilaniD· 2 shared Allyson Berent· 1 shared Baraa Abudiab· 1 shared Dania AbdellatifiD· 1 shared Prince Kumar SinghiD· 1 shared Rania AkkawiiD· 1 shared Srinivasarao RepudiiD· 1 shared Takwa Jebara· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersNeuroscience

Rami I. AqeilanORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintAug 17, 2026

Modeling and targeting haploinsufficiency in SHINE syndrome

Dania Abdellatif, Mustafa Obeid, Rami I. Aqeilan

This study models DLG4 mutations in SHINE syndrome using iPSC-derived neurons, showing PSD-95 deficiency and electrophysiological changes, and demonstrates rescue via AAV9-mediated gene delivery.

DOI 10.64898/2026.08.07.743528

humanexperimental assay

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NeuroscienceMolecular Therapy AdvancesPeer-reviewedJun 19, 2026

Neuron-Specific WWOX Gene Therapy Produces Dose-Dependent, Durable Rescue in a Model of WWOX-Related Epileptic Encephalopathy

Mustafa Obeid, Rania Akkawi, Srinivasarao Repudi…·Rami I. Aqeilan

This study identifies optimal parameters for neuron-targeted WWOX gene therapy in a mouse model of WWOX-related epileptic encephalopathy, showing durable rescue with a defined therapeutic window and dose.

4 citationstop 1%

mouseexperimental assay

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