BioengineeringbioRxivPreprint
The Role Of Fzd8 For Bone Development And Homeostasis In A Mouse Model Generated By CRISPR/Cas9 Genome Editing
Zhengkun Lin, Jianquan He, Hui Huang…·Jian‐Min Chen
This study generates an Fzd8-knockout mouse model using CRISPR/Cas9 to investigate its role in bone development and homeostasis, finding altered osteoclast and osteoblast activity and potential links to osteoporosis.
DOI 10.1101/2025.01.19.633799