Author

William Jobson Pargeter

University of FreiburgORCID 0009-0001-3109-6899Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:ChIP-seq· 1 Approach:contrastive learning· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Alexander MitrofanoviD· 1 shared Dominik RabschiD· 1 shared Masako Monika KaufmanniD· 1 shared Michael UhliD· 1 shared Rolf BackofeniD· 1 shared Thomas BroxiD· 1 shared Toni CathomeniD· 1 shared Van Dinh TraniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBioinformatics

Alexander MitrofanovORCID

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintOct 11, 2026

CRISCross: Integration of Epigenetic Information for Deep-Learning-Based Prediction of CRISPR-Cas9 Off-Targets Across Cell Types

William Jobson Pargeter, Dominik Rabsch, Masako Monika Kaufmann…·Rolf Backofen

CRISCross improves CRISPR-Cas9 off-target prediction by integrating epigenetic features with sequence data across cell types, showing better performance than sequence-only models.

DOI 10.64898/2026.10.09.757843

DNA methylationChIP-seq

𝕏 PostBluesky