Author

Dominik Rabsch

University of FreiburgORCID 0000-0001-6701-7753Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Approach:contrastive learning· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Rolf BackofeniD· 2 shared Alexander MitrofanoviD· 1 shared Dörte BecheriD· 1 shared Halie Rae Ropp· 1 shared Jürgen BarteliD· 1 shared Luisa HemmiD· 1 shared Manuel Brenes‐ÁlvareziD· 1 shared Masako Monika KaufmanniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBioinformatics

Rolf BackofenORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintOct 11, 2026

CRISCross: Integration of Epigenetic Information for Deep-Learning-Based Prediction of CRISPR-Cas9 Off-Targets Across Cell Types

William Jobson Pargeter, Dominik Rabsch, Masako Monika Kaufmann…·Rolf Backofen

CRISCross improves CRISPR-Cas9 off-target prediction by integrating epigenetic features with sequence data across cell types, showing better performance than sequence-only models.

DOI 10.64898/2026.10.09.757843

DNA methylationChIP-seq

𝕏 PostBluesky

BioinformaticsNature CommunicationsPeer-reviewedSep 26, 2025

RAPDOR: Using Jensen-Shannon Distance for the computational analysis of complex proteomics datasets

Luisa Hemm, Dominik Rabsch, Halie Rae Ropp…·Rolf Backofen

RAPDOR uses Jensen-Shannon distance to analyze complex proteomics datasets, identifying RNA-binding proteins in cyanobacteria and showing its utility in stress-induced protein redistribution.

5 citations

proteomicsstatistical model

𝕏 PostBluesky