Author

Leonardo Betancurt-Anzola

Centre National de la Recherche ScientifiqueORCID 0009-0001-3475-7306Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2

Frequent Co-Authors

Marc H. DelarueiD· 2 shared Andrew F. GardneriD· 1 shared Kelly M. ZatopekiD· 1 shared Ludovic SauguetiD· 1 shared Markel Martínez‐CarranzaiD· 1 shared Nilesh B. KaralkariD· 1 shared Richard T. PomerantziD· 1 shared Steven A. BenneriD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersSynthetic Biology

Marc H. DelarueORCID

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2 papers

Recent·Most cited

Template-Independent Enzymatic RNA Synthesis

Nilesh B. Karalkar, Tatiana Kent, Taylor Tredinnick, Leonardo Betancurt-Anzola, Marc H. Delarue, Richard T. Pomerantz, Steven A. Benner

This paper introduces a method for template-independent enzymatic RNA synthesis using modified nucleotides and DNA polymerases, enabling the creation of RNA with defined sequences without traditional chemical synthesis limitations.

bioRxiv · Oct 9, 2024 · PreprintSynthetic Biology

Molecular basis for proofreading by the unique exonuclease domain of Family-D DNA polymerases

Leonardo Betancurt-Anzola, Markel Martínez‐Carranza, Marc H. Delarue, Kelly M. Zatopek, Andrew F. Gardner, Ludovic Sauguet

The paper presents cryo-EM structures of Family-D DNA polymerases in a proofreading mode, revealing a novel correction mechanism and the role of their unique exonuclease domain.

Nature Communications · Dec 14, 2023Peer-reviewedMolecular Biology