Author
Foundation for Applied Molecular EvolutionORCID 0000-0002-3318-9917Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Ruolin Ma, Michael Brazzill, Dylan Justice, Nicholas Buckham, Cen Chen, Shuichi Hoshika, Steven A. Benner, David A. Rusling
This paper demonstrates that Z-modified TFOs can repress endogenous gene expression by forming stable triplexes at GC-rich regulatory elements.
Nucleic Acids Research · Oct 13, 2026Peer-reviewedCell Biology
Caitlin Walters-Freke, Shuichi Hoshika, Alexandra Perry, Steven A. Benner, Renwick C. J. Dobson, Zachary D. Tillett, Nigel G. J. Richards, Adele Williamson
The paper investigates how DNA ligases handle non-canonical base pairs in hachimoji DNA, finding that consecutive non-canonical bases at the 3-end reduce ligation efficiency.
bioRxiv · Jul 1, 2026 · PreprintBiochemistry
Nilesh B. Karalkar, Tatiana Kent, Taylor Tredinnick, Leonardo Betancurt-Anzola, Marc H. Delarue, Richard T. Pomerantz, Steven A. Benner
This paper introduces a method for template-independent enzymatic RNA synthesis using modified nucleotides and DNA polymerases, enabling the creation of RNA with defined sequences without traditional chemical synthesis limitations.
bioRxiv · Oct 9, 2024 · PreprintSynthetic Biology
Roberto Laos, Steven A. Benner
The paper develops fluorinated oils with water-like density and surfactants to create stable droplets for synthetic biology applications.
PLoS ONE · Jan 20, 2022Peer-reviewedSynthetic Biology