Systems BiologyThe Journal of ImmunologyPeer-reviewed
Network analysis reveals a distinct axis of macrophage activation in response to conflicting inflammatory cues
Xiaji Liu, Jingyuan Zhang, Angela C. Zeigler…·Jeffrey J. Saucerman
The paper develops a computational model of macrophage signaling to predict activation responses to cytokine combinations, revealing a second axis of activation distinct from the M1-M2 polarization.
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