Author
University of VirginiaORCID 0000-0002-1552-2464Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Anders R. Nelson, Steven L. M. Christiansen, Kristen M. Naegle, Jeffrey J. Saucerman
The paper uses high-content imaging and a new computational model to predict how drugs affect cardiac fibroblast phenotype and identify potential therapeutic mechanisms.
Xiaji Liu, Jingyuan Zhang, Angela C. Zeigler…·Jeffrey J. Saucerman
The paper develops a computational model of macrophage signaling to predict activation responses to cytokine combinations, revealing a second axis of activation distinct from the M1-M2 polarization.
Angela C. Zeigler, Anders R. Nelson, Anirudha S. Chandrabhatla…·Jeffrey J. Saucerman
The paper develops a computational model to simulate fibroblast signaling and fibrosis after myocardial infarction, revealing how paracrine stimuli and signaling pathways drive fibroblast phenotype dynamics.