Cell BiologyNucleic Acids ResearchPeer-reviewed
Sequence-Specific Targeting of GC-Rich Gene Loci by Parallel Triplex-Forming Oligonucleotides Containing a Modified Nucleobase
Ruolin Ma, Michael Brazzill, Dylan Justice…·David A. Rusling
This paper demonstrates that Z-modified TFOs can repress endogenous gene expression by forming stable triplexes at GC-rich regulatory elements.
DOI 10.1093/nar/gkag998