Jeremy J. Lambert

The role of opioid receptors in tianeptine-induced beta oscillations and memory enhancement

This study investigates how tianeptine affects memory and brain oscillations in mice, finding that mu-opioid receptors mediate beta oscillations while both mu- and delta-opioid receptors are needed for memory enhancement.

The atypical antidepressant tianeptine causes opioid-receptor-dependent beta oscillations in the rat hippocampus

The paper investigates how the antidepressant tianeptine affects beta oscillations in the rat hippocampus through opioid receptor mechanisms.

The atypical antidepressant and cognitive enhancer tianeptine disinhibits hippocampal CA1 pyramidal neurons by reducing GABAergic neurotransmission

This study investigates tianeptine's effects on hippocampal CA1 neurons, showing it reduces GABAergic neurotransmission and disinhibits pyramidal neurons, but not through simple GABA blockade.

Impaired developmental microglial pruning of excitatory synapses on CRH-expressing hypothalamic neurons exacerbates stress responses throughout life

The paper shows that early-life adversity impairs microglial pruning of excitatory synapses on CRH-expressing hypothalamic neurons, leading to heightened stress responses later in life.

Identification of amyloid beta oligomers in locus coeruleus (LC) neurons of Alzheimer's patients and their impact on LC oxidative stress, inhibitory neurotransmitter receptors and neuronal excitability