Judith Armstrong

This study evaluates epigenetic clocks for aging interventions, finding newer clocks trained on mortality or aging rates are more reliable than those based on chronological age.

CpG Atlas integrates over 1.2 million CpG sites across multiple methylation arrays with 18 annotation layers and provides a query interface for epigenetic research.

TranslAGE provides a standardized framework for benchmarking epigenetic aging biomarkers by harmonizing datasets and precomputing scores across multiple performance domains.

CpGPT is a foundation model for DNA methylation analysis that outperforms specialized models in aging-related tasks and can impute methylation profiles across diverse conditions.

This study evaluates the responsiveness of DNA methylation aging biomarkers across 51 longevity interventions, identifying factors influencing their response and highlighting the utility of explainable clocks.