Author

Samhita Pal

Vanderbilt University Medical CenterORCID 0009-0001-4930-916XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

Amir AsiaeeiD· 2 shared Heather H. PuaiD· 2 shared James P. LongiD· 2 shared Kevin R. CoombesiD· 2 shared Jared StrauchiD· 1 shared Leila Azinfar· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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2 shared papersBioinformatics

Amir AsiaeeORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintApr 5, 2026

Widespread data leakage inflates accuracy and corrupts biomarker discovery in cancer drug response prediction

Amir Asiaee, Jared Strauch, Leila Azinfar…·Kevin R. Coombes

The paper shows that data leakage in drug response prediction models inflates accuracy and corrupts biomarker discovery, and provides a solution to avoid this issue.

2 citations

statistical modelbenchmarking

𝕏 PostBluesky

BioinformaticsbioRxivPreprintMar 30, 2026

A shape-constrained regression and wild bootstrap framework for reproducible drug synergy testing

Amir Asiaee, James P. Long, Samhita Pal…·Kevin R. Coombes

SIR improves drug synergy testing by using shape-constrained regression and bootstrap methods to provide reliable statistical inference and error control.

DOI 10.64898/2026.02.05.704019

statistical modeldrug response / drug discovery

𝕏 PostBluesky