Cancer BiologybioRxivPreprint
MCT1 activity defines an aggressive metabolic phenotype and therapeutic target in non-small cell lung cancer
Robert B Cameron, Kristen Erika Shema, Nathan Dubois…·Brandon Faubert
This study shows that MCT1-mediated lactate uptake sustains nucleotide homeostasis in NSCLC, and its inhibition enhances chemotherapy efficacy by exposing a metabolic vulnerability.
DOI 10.64898/2026.09.20.752999