Author

Christine M. Bestvina

University of ChicagoORCID 0000-0001-7189-1590Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1

Frequent Co-Authors

Marina C. Garassino· 2 shared Alessandra EspositoiD· 1 shared Alexander GuzzettaiD· 1 shared Aliya HusainiD· 1 shared Alpaslan TasdoganiD· 1 shared Anna Di LelloiD· 1 shared Apameh Pezeshk· 1 shared Arjun RamaniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Marina C. Garassino

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 22, 2026

MCT1 activity defines an aggressive metabolic phenotype and therapeutic target in non-small cell lung cancer

Robert B Cameron, Kristen Erika Shema, Nathan Dubois…·Brandon Faubert

This study shows that MCT1-mediated lactate uptake sustains nucleotide homeostasis in NSCLC, and its inhibition enhances chemotherapy efficacy by exposing a metabolic vulnerability.

DOI 10.64898/2026.09.20.752999

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologyCell Reports MedicinePeer-reviewedAug 28, 2026

Conserved principles of spatial biology define tumor heterogeneity and response to immunotherapy

Vivek Behera, Alexander Guzzetta, Hannah Giba…·Arjun Raman

This study identifies conserved spatial structures in tumors that predict immune response, using a classification framework based on transcriptional covariation.

DOI 10.1016/j.xcrm.2026.103013

humanbulk RNA-seq

𝕏 PostBluesky