Author

Jack T. Horst

Dana-Farber Cancer InstituteORCID 0009-0001-5854-1825Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Toni K. ChoueiriiD· 3 shared Aaron R. ThorneriD· 2 shared Eliezer M. Van AlleniD· 2 shared Jiao LiiD· 2 shared Prathyusha KondaiD· 2 shared Rachel Trowbridge· 2 shared Sabrina Yvonne CampiD· 2 shared Srinivas Raghavan ViswanathaniD· 2 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersGenomics

Toni K. ChoueiriORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

GenomicsNature CommunicationsPeer-reviewedAug 26, 2026

Fusion-driven oncogenic programs shape the immune landscape in translocation renal cell carcinoma

Prathyusha Konda, Alexandra J. Wakolbinger, Yantong Cui…·Srinivas Raghavan Viswanathan

This study identifies fusion-driven oncogenic programs in translocation renal cell carcinoma (tRCC) that shape an immunosuppressive tumor microenvironment, explaining its reduced immunotherapy response.

2 citationstop 4%

humanscRNA-seq

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Cancer BiologyScience AdvancesPeer-reviewedFeb 20, 2026

Single-cell epigenetic profiling reveals an interferon response-high program associated with BAP1 deficiency in kidney cancer

Sabrina Yvonne Camp, Meng Xiao He, Michael S. Cuoco…·Eliezer M. Van Allen

The paper identifies an IFN response-high epigenetic program linked to BAP1 deficiency in kidney cancer using single nucleus ATAC sequencing across multiple cohorts.

8 citationstop 1%

humanscATAC-seq

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GenomicsJournal of Clinical InvestigationPeer-reviewedFeb 1, 2026

Detection and monitoring of translocation renal cell carcinoma via plasma cell-free epigenomic profiling

Simon Garinet, Karl Semaan, Jiao Li…·Srinivas Raghavan Viswanathan

This paper detects and monitors translocation renal cell carcinoma (tRCC) using plasma cell-free epigenomic profiling, achieving high accuracy in distinguishing tRCC from other cancers and healthy controls.

7 citationstop 1%

humanDNA methylation

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