Author

Yusen Hou

The Hong Kong University of Science and Technology (Guangzhou)ORCID 0009-0001-6526-9727Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 3 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 4 Approach:deep learning· 3 Assay:Hi-C· 3 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Yanlin ZhangiD· 4 shared Weicai LongiD· 3 shared Houcheng SuiD· 2 shared Audrey BaguetteiD· 1 shared Chengrui WangiD· 1 shared Haojie LuiD· 1 shared Jinming YangiD· 1 shared Jixin YangiD· 1 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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4 shared papersBioinformatics

Yanlin ZhangORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

BioMaster: Multi-agent System for Automated Bioinformatics Analysis Workflow

Houcheng Su, Junning Feng, Yawen Lu, Yucheng Xu, Jinming Yang, Haojie Lu, Jixin Yang, Xu Yang, Sirui Xie, Weicai Long, Chengrui Wang, Yusen Hou, Tingyu Zhu, Yanlin Zhang

BioMaster automates complex bioinformatics workflows using a multi-agent system, improving accuracy, efficiency, and scalability across tasks like RNA-seq and Hi-C processing.

Patterns · Aug 14, 2026Peer-reviewedBioinformatics

ContextTAD: Context-aware boundary learning for TAD calling from Hi-C contact maps

Weicai Long, Yusen Hou, Yanlin Zhang

ContextTAD improves TAD calling from Hi-C contact maps by learning context-aware boundary evidence, achieving strong performance across multiple evaluation settings.

bioRxiv · May 13, 2026 · PreprintGenomics

PopGenAgent: An Agent-Mediated Workflow for Population Genetics Analyses

Houcheng Su, Weicai Long, Juning Feng, Yusen Hou, Yanlin Zhang

PopGenAgent streamlines population genetics analyses by organizing tasks into a structured workflow, enabling reproducible and transparent multi-step analyses with preserved intermediate results.

bioRxiv · Apr 1, 2026 · PreprintBioinformatics

A universal tool for chromatin loop annotation in bulk and single-cell Hi-C data

Yusen Hou, Audrey Baguette, Mathieu Blanchette, Yanlin Zhang

Polaris is a tool for chromatin loop annotation in bulk and single-cell Hi-C data that outperforms existing methods across different datasets and conditions.

bioRxiv · Dec 24, 2024 · PreprintBioinformatics