Molecular BiologyLife Science AlliancePeer-reviewed
CLN3 deficiency leads to neurological and metabolic perturbations during early development
Ursula Heins-Marroquin, Randolph R. Singh, Simon Perathoner…·Carole L. Linster
This study shows that CLN3 deficiency in zebrafish leads to metabolic changes, including GPD accumulation and BMP reduction, and confirms these findings in human stem cell models.
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