Author

Alexander D. Crawford

University of Luxembourg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Organism:zebrafish· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:metabolomics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

María Lorena Cordero-MaldonadoiD· 2 shared Simon PerathoneriD· 2 shared Ursula Heins-MarroquiniD· 2 shared Anaïs CarpentieriD· 1 shared Annemarie H. MeijeriD· 1 shared Carla MerinoiD· 1 shared Carole L. LinsteriD· 1 shared Christian JägeriD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersMolecular Biology

María Lorena Cordero-MaldonadoORCID

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Author profile →

2 papers

Recent·Most cited

CLN3 deficiency leads to neurological and metabolic perturbations during early development

Ursula Heins-Marroquin, Randolph R. Singh, Simon Perathoner, Floriane Gavotto, Carla Merino, Myrto Patraskaki, Gemma Gomez‐Giro, Felix Bruno Kleine Borgmann, Melanie Meyer, Anaïs Carpentier, Marc O. Warmoes, Christian Jäger, Michel Guy André Mittelbronn, Jens Christian Schwamborn, María Lorena Cordero-Maldonado, , Carole L. Linster

This study shows that CLN3 deficiency in zebrafish leads to metabolic changes, including GPD accumulation and BMP reduction, and confirms these findings in human stem cell models.

Life Science Alliance · Jan 9, 2024Peer-reviewedMolecular Biology

Deep learning image recognition enables efficient genome editing in zebrafish by automated injections

María Lorena Cordero-Maldonado, Simon Perathoner, K.-J. van der Kolk, Ralf Boland, Ursula Heins-Marroquin, Herman P. Spaink, Annemarie H. Meijer, Alexander D. Crawford, Jan de Sonneville

This paper develops a deep learning system for automated microinjection in zebrafish embryos, achieving efficiency comparable to manual methods and enabling high-throughput genome editing.

PLoS ONE · Jan 7, 2019Peer-reviewedMolecular Biology