Author

Gianluca Christos Kikidis

Johns Hopkins UniversityORCID 0009-0001-6979-7404Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 5 Organism:human· 5 Approach:statistical model· 5 Research Focus:differential expression· 4 Research Focus:gene regulatory network inference· 3 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:eQTL / molecular QTL mapping· 1

Frequent Co-Authors

Giulio PergolaiD· 5 shared Alessandro BertolinoiD· 4 shared Christopher BorcukiD· 4 shared Daniel R. WeinbergeriD· 4 shared Leonardo SportelliiD· 4 shared Antonio RampinoiD· 3 shared Joel E. KleinmaniD· 3 shared Madhur ParihariD· 3 shared

Activity by Year

2023-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersGenomics

Giulio PergolaORCID

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5 papers

Recent·Most cited

GenomicsbioRxivPreprintJun 11, 2026

Liquidity of gene co-expression trajectories across the lifespan highlights delayed maturation and the perinatal GABA switch in schizophrenia risk

Loredana Bellantuono, Fabio Di Camillo, Christopher Borcuk…·Giulio Pergola

The paper uses a novel 'liquidity' metric to analyze gene expression trajectories across lifespan, revealing delayed maturation and perinatal GABA switch in schizophrenia risk without detectable neuropathology.

1 citation

humanbulk RNA-seq

GenomicsbioRxivPreprintMay 19, 2026

Genetic Risk and Resilience for Schizophrenia Stratified by Perinatal Gene Expression Predict Adult Cognitive Performance

Gianluca Christos Kikidis, Alessandra Raio, Leonardo Sportelli…·Giulio Pergola

The paper examines how schizophrenia genetic risk and resilience variants, co-expressed in the human brain, are associated with cognitive performance across development in 16,520 individuals.

1 citation

humanbulk RNA-seq

GenomicsbioRxivPreprintFeb 11, 2026

Co-expression-based models improve eQTL predictions and highlightnovel transcriptome-wide genes associated with schizophrenia

Fabiana Rossi, Leonardo Sportelli, Gianluca Christos Kikidis…·Giulio Pergola

The paper introduces co-expression-based models to improve eQTL predictions and identifies novel schizophrenia-associated genes using brain RNA-seq data.

DOI 10.64898/2026.02.10.704353

humanbulk RNA-seq

NeurosciencebioRxivPreprintJun 12, 2024

Transcriptomics and proteomics of projection neurons in a circuit linking hippocampus with dorsolateral prefrontal cortex in the human brain

Christopher Borcuk, Rahul A. Bharadwaj, Gianluca Christos Kikidis…·Giulio Pergola

The paper analyzes transcriptomic and proteomic data from specific brain regions to identify molecular changes in schizophrenia, showing superior regional discrimination in transcriptomic and proteomic data.

1 citation

humanbulk RNA-seq

NeuroscienceBiological Psychiatry Cognitive Neuroscience and NeuroimagingPeer-reviewedNov 22, 2023

A miR-137-related biological pathway of risk for Schizophrenia is associated with human brain emotion processing

Giulio Pergola, Antonio Rampino, Leonardo Sportelli…·Alessandro Bertolino

The paper links miR-137 and its target genes to schizophrenia risk through emotion processing in the prefrontal cortex, showing allele associations with brain activation patterns.

15 citations

humanbulk RNA-seq