Author

Huaiyuan Cai

Huazhong Agricultural UniversityORCID 0009-0001-7668-7676Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Research Focus:software / tool· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Assay:imaging· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Weize XuiD· 2 shared Florian MuelleriD· 1 shared Gang CaoiD· 1 shared Gang CaoiD· 1 shared Jiahao ZhangiD· 1 shared Lingkai ZhangiD· 1 shared Qian ZhangiD· 1 shared Qian ZhangiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBioinformatics

Weize XuORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintApr 15, 2026

U-Probe: universal agentic probe design for imaging-based spatial-omics

Qian Zhang, Huaiyuan Cai, Jiahao Zhang…·Weize Xu

U-Probe is a universal probe design platform that enables agentic, AI-assisted creation of FISH probes for spatial-omics applications, validated across multiple scenarios.

DOI 10.64898/2026.04.12.717982

mousespatial transcriptomics

𝕏 PostBluesky

BioinformaticsbioRxivPreprintMar 6, 2024

U-FISH: a universal deep learning approach for accurate FISH spot detection across diverse datasets

Weize Xu, Huaiyuan Cai, Qian Zhang…·Gang Cao

U-FISH improves FISH spot detection accuracy and generalization using a deep learning approach with a U-Net model and a large annotated dataset.

5 citations

imagingdeep learning

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