Author

Sedat Dogru

Johns Hopkins UniversityORCID 0009-0001-8037-666XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Aleksander S. PopeliD· 1 shared Anshu Marathe· 1 shared Ashwatha Suresh· 1 shared Azher M. Hussain· 1 shared Edward P. Bowman· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperPharmacology & Toxicology

Aleksander S. PopelORCID

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1 paper

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintSep 25, 2026

Quantitative Systems Pharmacology Model for Trop-2 Targeting Antibody-Drug Conjugate in Triple-Negative Breast Cancer

Sedat Dogru, Ashwatha Suresh, Edward P. Bowman…·Aleksander S. Popel

This paper develops a QSP model to simulate TROP2-targeted ADC efficacy in TNBC, showing tumor heterogeneity and payload pharmacokinetics drive response.

DOI 10.64898/2026.09.20.752985

humanstatistical model

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