Marie-Pierre Mailhé

The paper identifies distinct roles for embryonic multipotent progenitors (eMPP) and hematopoietic stem cells (HSC) in fetal hematopoiesis and immune system development.

The paper identifies the spatiotemporal dynamics of cytokine expression in fetal liver hematopoiesis, showing that hepatoblasts and mesothelial cells produce key growth factors and cytokines.

The paper identifies fetal liver stromal subsets using spectral cytometry and autofluorescence, finding two distinct autofluorescent signals corresponding to hepatoblasts/cholangiocytes and stellate cells.

The paper identifies a triad of myeloid cells and endothelial cells that collaborate to produce PGE2 and expand hematopoietic stem cells in the fetal niche.

The paper uses whole-organism single-cell RNA-seq to analyze cell type diversity in Nematostella vectensis, identifying 35% of genes and 51% of TFs as cell type-specific.