Author

Srijith Sasikumar

Indian Institute of Technology MadrasORCID 0009-0001-9244-4359Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:differential expression· 2 Organism:yeast· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Assay:metabolomics· 1 Assay:metagenomics· 1

Frequent Co-Authors

Himanshu SinhaiD· 3 shared Bharath PrithivirajiD· 1 shared Karthik RamaniD· 1 shared Nirav BhattiD· 1 shared Rajeeva R. M. Lokshanan· 1 shared S Pavan KumariD· 1 shared Shannara Kayleigh Taylor ParkinsiD· 1 shared Suresh SudarsaniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersSystems Biology

Himanshu SinhaORCID

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3 papers

Recent·Most cited

Microbial communities on station and train surfaces in Chennai Metro: Insights into urban transit microbiome

Vijaya Yuvaram Singh, Veerendra P. Gadekar, Srijith Sasikumar, Rajeeva R. M. Lokshanan, V. Senthamizhan, Bharath Prithiviraj, Himanshu Sinha, Karthik Raman

The paper characterizes microbial communities and AMR genes in Chennai Metro surfaces, finding distinct profiles and low AMR prevalence.

mSphere · Oct 8, 2026Peer-reviewedEcology

Interaction of Genetic Variants Activates Latent Metabolic Pathways in Yeast

Srijith Sasikumar, Shannara Kayleigh Taylor Parkins, Suresh Sudarsan, Himanshu Sinha

The paper investigates how genetic variant interactions in yeast activate latent metabolic pathways and modulate phenotypic outcomes during sporulation.

Nature Communications · Aug 27, 2025Peer-reviewedSystems Biology

Genome-Scale Metabolic Modeling Identifies Causal Reactions Mediated by SNP-SNP Interactions Influencing Yeast Sporulation

Srijith Sasikumar, S Pavan Kumar, Nirav Bhatt, Himanshu Sinha

The paper uses genome-scale metabolic models to identify causal reactions influenced by SNP-SNP interactions affecting yeast sporulation efficiency.

npj Systems Biology and Applications · May 20, 2025Peer-reviewedSystems Biology