Himanshu Sinha

The paper characterizes microbial communities and AMR genes in Chennai Metro surfaces, finding distinct profiles and low AMR prevalence.

The paper presents a comprehensive genomic atlas of Indian populations, identifying novel variants and highlighting genetic diversity and pharmacogenomic implications.

The paper develops an interpretable machine learning framework to decode genotype-phenotype maps in yeast, identifying causal genes and pathway enrichments from QTL data.

This study investigates ibuprofen-antifungal interactions, finding that outcomes depend on fungal strain genetics, nutrient environment, and assay type, with ibuprofen-clotrimazole showing antagonism and ibuprofen-caspofungin showing synergy or additivity.

The paper investigates how genetic variant interactions in yeast activate latent metabolic pathways and modulate phenotypic outcomes during sporulation.

GViNC compares genome graphs to reveal ancestry-specific genetic diversity patterns and key variant regions in human populations.

This study maps ribosomal protein (RP) gene expression across human tissues using single-cell RNA sequencing, revealing tissue-specific patterns and linking RP heterogeneity to reproductive health and anaemia.

The paper uses genome-scale metabolic models to identify causal reactions influenced by SNP-SNP interactions affecting yeast sporulation efficiency.

SCI-VCF provides a GUI tool for summarizing, comparing, inspecting, and visualizing variant call format data without requiring programming expertise.

Panera improves microbial community metabolic modeling by integrating 16S data with pan-genus models, reducing prediction error by 10%.

This study shows MKT1 alleles modulate stress responses by stabilizing Puf3-target mitochondrial genes, with PBP1 and PUF3 playing key roles in this regulation.

The paper uses network theory on longitudinal gene expression data to identify key genes affecting sporulation efficiency in yeast.

The paper shows ribosomal proteins function in modular, environment-specific ways across yeast, mice, and humans, adapting to different ecological niches and tissue microenvironments.

The paper investigates the functional consequences of a rare TAO3 variant in yeast, revealing its meiotic role and identifying new regulators of sporulation efficiency.