Author

Christopher R. Pretz

Guardant (United States)ORCID 0009-0001-9335-7468Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:human· 1 Approach:mixed model· 1 Approach:statistical model· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Amar K. DasiD· 1 shared Caroline M. WeipertiD· 1 shared Jiemin LiaoiD· 1 shared Leslie A. BucheitiD· 1 shared Leylah M. DrusboskyiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperGenomics

Amar K. DasORCID

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1 paper

Recent·Most cited

GenomicsbioRxivPreprintApr 3, 2025

A Proposed Statistical Approach for Conducting Longitudinal Assessment of Circulating Tumor DNA

Christopher R. Pretz, Jiemin Liao, Caroline M. Weipert…·Amar K. Das

This paper proposes a statistical framework using hierarchical mixed-effects models to analyze ctDNA dynamics in liquid biopsy data, finding that a hierarchical linear spline model best captures patient-level ctDNA evolution.

DOI 10.1101/2025.04.03.646973

humanDNA methylation

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