Cell BiologyNature CommunicationsPeer-reviewed
Cryo-EM of PMEL Amyloids Reveals Pathogenic Mechanism of Pigment Dispersion Syndrome
Haruaki Yanagisawa, Harumi Arai, Tony Wang…·Toshiyuki Oda
The paper determines the structure of PMEL amyloids using cryo-EM and shows how the G175S mutation increases amyloid formation, contributing to pigment dispersion syndrome.