Author

Li Chen

University of MinnesotaORCID 0009-0002-0136-0238Unclaimed ORCID profile · follow to get notified of new preprints

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Li Chen14 papers · Northwestern University

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Organism:human· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Chunlin LiiD· 1 shared Peng WeiiD· 1 shared Tianzhong YangiD· 1 shared Zhichao XuiD· 1 shared Zhiyu Kang· 1 shared

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2025-2025 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperGenomics

Chunlin LiORCID

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1 paper

Recent·Most cited

GenomicsbioRxivPreprintJan 28, 2025

Estimation of total mediation effect for a binary trait in a case-control study for high-dimensional omics mediators

Zhiyu Kang, Li Chen, Peng Wei…·Tianzhong Yang

The paper introduces an R2 total mediation effect measure for binary traits in case-control studies with high-dimensional mediators, showing 89% of BMI's effect on CHD is mediated by metabolomics.

DOI 10.1101/2025.01.28.635396

humanmetabolomics

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