Author

Stephen M Burleigh

ORCID 0009-0002-0693-8158Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

Brian J. BoothiD· 2 shared Lina R Bagepalli· 2 shared Lucia R. ShumakeriD· 2 shared Yiannis A. SavvaiD· 2 shared Yingxin CaoiD· 2 shared Yue JiangiD· 2 shared Adrian W. BriggsiD· 1 shared Alexander J. LetiziaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersNeuroscience

Brian J. BoothORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJun 28, 2026

Rett syndrome lifespan extension in mice via AI-guided ADAR editing

Yiannis A. Savva, Brian J. Booth, Lucia R. Shumaker…·Alison VanSchoiack

This paper uses AI-guided ADAR editing to correct a nonsense mutation in mice, improving Rett syndrome symptoms and extending lifespan.

DOI 10.64898/2026.06.23.734060

mousedeep learning

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BioengineeringbioRxivPreprintDec 20, 2025

Helix: a structure-aware deep learning model for accurate prediction of A-to-I RNA editing by endogenous ADARs

Yingxin Cao, Lina R Bagepalli, Yiannis A. Savva…·Yue Jiang

Helix predicts A-to-I RNA editing by ADARs with high accuracy using a structure-aware transformer model, enabling efficient gRNA design for therapeutic applications.

1 citation

humanbulk RNA-seq

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