Author

Jay A. Gottfried

University of PennsylvaniaORCID 0009-0002-0787-8513Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Assay:electronic health records· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:imaging· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1

Frequent Co-Authors

John A. DetreiD· 2 shared Ludwig Sichen ZhaoiD· 2 shared Matthew Dylan TisdalliD· 2 shared Alister Virkler· 1 shared Andrew I. YangiD· 1 shared Clara U. RaitheliD· 1 shared Gülce Nazlı DikeçligiliD· 1 shared H. Isaac CheniD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersBioengineering

John A. DetreORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

MR KLEAN: a Generalized Acquisition-agnostic LLR k-Space Denoising Method for High-dimensional Imaging

Ludwig Sichen Zhao, Manuel Taso, Jay A. Gottfried, John A. Detre, Matthew Dylan Tisdall

MR KLEAN improves MRI image quality by denoising k-space data without relying on specific acquisition or reconstruction methods.

bioRxiv · Apr 9, 2026 · PreprintBioengineering

Direct piriform-to-auditory cortical projections shape auditory-olfactory integration

Nathan W. Vogler, Ruoyi Chen, Alister Virkler, Violet Y. Tu, Jay A. Gottfried, Maria Neimark Geffen

This study identifies a direct piriform-to-auditory cortical circuit that modulates auditory responses to odors in mice.

Journal of Neuroscience · Nov 7, 2024Peer-reviewedNeuroscience

Leveraging Multi-Echo EPI to Enhance BOLD Sensitivity in Task-based Olfactory fMRI

Ludwig Sichen Zhao, Clara U. Raithel, Matthew Dylan Tisdall, John A. Detre, Jay A. Gottfried

This study develops a ME-EPI protocol for olfactory task-based fMRI, showing improved BOLD sensitivity over 1E-EPI through signal combination and artifact reduction.

Imaging Neuroscience · Jan 1, 2024Peer-reviewedNeuroscience

Odor representations from the two nostrils are temporally segregated in human piriform cortex

Gülce Nazlı Dikeçligil, Andrew I. Yang, Nisha Sanghani, Timothy H. Lucas, H. Isaac Chen, Kathryn A. Davis, Jay A. Gottfried

The paper shows that odor information from each nostril is encoded separately in the piriform cortex, with ipsilateral odors processed faster than contralateral ones.

Current Biology · Nov 3, 2023Peer-reviewedNeuroscience