Author

Chelsea B Darwin

Department of Genetics, University of Pennsylvania Perelman School of Medicine , 415 Curie Blvd, Philadelphia, PA 19104 , USAORCID 0009-0002-0928-7434Unclaimed ORCID profile · follow to get notified of new preprints

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Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1

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Meera V. SundaramiD· 2 shared Helen SchmidtiD· 1 shared Nicholas D SerraiD· 1 shared

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2023-2024 · peak 1/yr

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3 top collaborators · 2 mutual co-author links

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2 shared papersDevelopmental Biology

Meera V. SundaramORCID

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2 papers

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Developmental BiologyDevelopmental BiologyPeer-reviewedNov 1, 2024

The Pax transcription factor EGL-38 links EGFR signaling to assembly of a cell-type specific apical extracellular matrix in the Caenorhabditis elegans vulva

Helen Schmidt, Chelsea B Darwin, Meera V. Sundaram

The paper investigates how the Pax transcription factor EGL-38 regulates cell-type specific assembly of the apical extracellular matrix in C. elegans vulva cells.

5 citations

C. elegansexperimental assay

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Cell BiologybioRxivDec 26, 2023

C. elegans Hedgehog-related proteins are tissue- and substructure-specific components of the cuticle and pre-cuticle

Nicholas D Serra, Chelsea B Darwin, Meera V Sundaram

This study identifies C. elegans Hedgehog-related proteins as components of the cuticle and pre-cuticle extracellular matrices, showing tissue- and substructure-specific associations and functional roles in matrix structure.

DOI 10.1093/genetics/iyae081

C. elegansexperimental assay

𝕏 PostBluesky